Third time's the charm
Raildex
Misaki has valid reasons to hate Misaka?
Misaka does nothing to Misaki.
Hell the first time Misaki ever showed up it was to remind Misaka to stay in her place and not try to make a clique right before she Mind controlled the library as a threat to remind Misaka who would be hurt if they fought.
Hey man she's crushing on Misakis crush, who can't remember her so she feels replaced. That's plenty of reason to hate someone, it just isnt a very valid one.
Yeah so now you're going back to to "Misaki has no reason to hate Mikoto" and we will be going circle because you're too much of a onions boy to admit you were wrong.
From their first interactions? I'd say she doesn't. She's basically just making sure Misaka knows she's top bitch in Tokiwadai. After that I'd say Misaka and Misaki give as good as they get from each other.