Doctor Octopus would be neat, especially if they're building up to the Sinister Six. Since all of Spider-Man's villains in the MCU seem to be connected to Iron Man, they could differentiate him from Vulture and Mysterio by having him actually respect Tony Stark's accomplishments with robotics and aspire to push it even further, leading to his accident.
Bryan Cranston would be a good choice. Great actor, can pull off both Otto's cold superiority and the petty visciousness, and he fits Sony's M.O. of always chasing A-listers for the lead villains (Michael Keaton, Jake Gyllenhaall, Michael Shannon, Matt Damon, etc.)
Only thing he doesn't have is Otto's physique, but then again, ultimate Doc Ock had a pretty average dadbod.
For my own selection for Spidey-3, I'm gonna advise a combo: JJJ returning as Jonah to bankroll Scorpion to prove Peter was behind the London attack, and bring him to Justice.
Meanwhile, Chameleon works to Peter for his own crimes, eventually taking Jonah's place in order to drive Scorpion to kill Peter completely.
I'd cast Doug Jones for Chameleon, and reuse Scorpion from Homecoming, and have a cameo of Keaton as the post credits hook.
If you're going to do Otto, I'd save it for the Sinister Six debut, merely being referred to as The Master Planner before that.
I'd cast Jonah Hill.
Daniel Gray
Bump What villains do you want to see in the future?
Xavier Nelson
Heisenberg with super human strength.
Andrew Roberts
We got Dmitri in Far From Home. Who not Sergei in the next one?
Why bother doing fan-casting for a sequel to a series with a notoriously awful cast? You could pick the best fit for the role anyone could imagine, but they still have to stand alongside the Breakfast Mutts.
